The money multiplier is the reciprocal of the reserve ratio. Under the assumption that banks do not hold excess reserves, the reserve ratio will be equal to the reserve requirement set by the Federal Reserve. For a reserve requirement of 20%, the reserve ratio is 1/5, and the multiplier is therefore 5. When the multiplier is 5, a banking system with $400 in reserves can support 5×$400=$2,000 in demand deposits.
If the reserve requirement falls from 20% to 10%, the reserve ratio falls from 1/5 to 1/10, and the multiplier rises from 5 to 10. At the lower reserve requirement, the banking system's $400 in reserves supports 10×$400=$4,000 in demand deposits.
For a given level of reserves, a higher reserve requirement is associated with a smaller money supply. At the higher reserve requirement, banks must hold a larger fraction of their deposits as reserves. This keeps more reserves away from the money creation process (it keeps new loans from being made, which would lead to more deposits, which would lead to more loans, and so on). Therefore, the higher the reserve requirement, the fewer demand deposits are generated in the money creation process from a given change in reserves.